LamPORE: rapid, accurate and highly scalable molecular screening for SARS-CoV-2 infection, based on nanopore sequencing

P. James, D. Stoddart, E. Harrington, J. Beaulaurier, L. Ly, S. Reid, D. Turner, S. Juul

medRxiv, 2020

LamPORE is a rapid way of testing/screening large numbers of samples for the presence or absence of SARS-CoV-2, the virus causing COVID-19. It combines barcoded multi-target amplification, 15-minute barcoded library preparation and real-time nanopore sequencing. Starting with extracted RNA, results can be obtained from 12 samples in approximately an hour and from 96 samples in under 2 hours. High scalability is achieved by combinatorial barcoding. Performance characteristics are currently being established and regulatory clearance to market is underway.

Cited by 28 publications.

Field of study: Medicine

10.1101/2020.08.07.20161737