Clinical manifestations of patients with Coronavirus Disease 2019 (COVID- 19) attending at hospitals in Bangladesh

M. Morshed, A. Mosabbir, P. Chowdhury, S. M. Ashadullah, M. Hossain

medRxiv, 2020

Bangladesh is in the rising phase of the ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, the scientific literature on clinical manifestations of COVID-19 patients from Bangladesh is virtually absent. This is the first study aimed to report the sociodemographic and clinical characteristics of patients with COVID-19 in Bangladesh. We conducted a cross-sectional study at three dedicated COVID-19 hospitals. A total of 103 RT-PCR confirmed non-critical COVID-19 patients were enrolled. Sociodemographic factors, underlying disease conditions, clinical symptoms and vital signs including oxygen saturation were documented and analyzed. The median age of the patients was 37 years (IQR: 31-53); most of the patients (71.8%) were male. Mild, moderate and severe illness were present in 74.76%, 9.71% and 15.53% of patients respectively. More than half (52.4%) patients had a co-morbidity, with hypertension being the most common (34%), followed by diabetes (21.4%) and Ischemic heart disease (9.7%). Fever (78.6%), weakness (68%) and cough (44.7%) were the most common clinical manifestations. Other common symptoms included loss of appetite (37.9%), difficulty breathing (37.9%), altered sensation of taste or smell (35.0%), headache (32%) and bodyache (32%). The median time from onset of symptom to attending hospitals was 7 days (IQR 4-10). This study will help both the clinicians and epidemiologists to understand the magnitude and clinical spectrum of COVID-19 patients in Bangladesh.

Cited by 5 publications.

Field of study: Medicine

10.1101/2020.07.30.20165100