M. Biasin, A. Bianco, G. Pareschi, A. Cavalleri, C. Cavatorta, C. Fenizia, P. Galli, L. Lessio, M. Lualdi, E. Tombetti, A. Ambrosi, E. Redaelli, I. Saulle, D. Trabattoni, A. Zanutta, M. Clerici
medRxiv, 2020
The potential virucidal effects of UV-C irradiation on SARS-CoV-2 were experimentally evaluated for different illumination doses and virus concentrations (1000, 5, 0.05 MOI). Both virus inactivation and replication inhibition were investigated as a function of these parameters. At a virus density comparable to that observed in SARS-CoV-2 infection, an UV-C dose of just 3.7 mJ/cm2 was sufficient to achieve a 3-log inactivation, and complete inhibition of all viral concentrations was observed with 16.9 mJ/cm2. These results could explain the epidemiological trends of COVID-19 and are important for the development of novel sterilizing methods to contain SARS-CoV-2 infection.
Cited by 31 publications.
Field of study: Medicine