BNT162b2 mRNA vaccination did not prevent an outbreak of SARS COV-2 variant 501Y.V2 in an elderly nursing home but reduced transmission and disease severity

Benoit Bailly, Luc Guilpain, K. Bouiller, C. Chirouze, Melissa N’debi, A. Soulier, V. Démontant, J. Pawlotsky, C. Rodriguez, S. Fourati

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021

Abstract We report an outbreak of SARS-CoV-2 501Y.V2 in a nursing home. All non-vaccinated residents (5/5) versus half of those vaccinated with BNT162b2 (13/26) were infected. Two of 13 vaccinated versus 4 of 5 non-vaccinated residents presented severe disease. BNT162b2 did not prevent the outbreak, but reduced transmission and disease severity.

Cited by 10 publications.

Field of study: Medicine

10.1093/cid/ciab446