Making Sense of Mutation: What D614G Means for the COVID-19 Pandemic Remains Unclear

N. Grubaugh, W. Hanage, A. Rasmussen

Cell, 2020

Abstract Korber et al. (2020) found that a SARS-CoV-2 variant in the spike protein, D614G, rapidly became dominant around the world. While clinical and in vitro data suggest that D614G changes the virus phenotype, the impact of the mutation on transmission, disease, and vaccine and therapeutic development are largely unknown.

Cited by 188 publications.

Field of study: Biology

10.1016/j.cell.2020.06.040